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Symbol
Name
ID
Eif4e
eukaryotic translation initiation factor 4E
MGI:95305
Phenotype annotations related to nervous system
Darker colors indicate more annotations
Human Phenotypes
EEG abnormality
Abnormal nonverbal communicative behavior
Delayed speech and language development
Lack of spontaneous play
Impaired ability to form peer relationships
Autism
Inflexible adherence to routines
Motor stereotypy
Restrictive behavior
Intellectual disability
Seizure
Disease(s) Associated with EIF4E
autistic disorder

Mouse Phenotypes
abnormal brain morphology
abnormal forebrain morphology
abnormal miniature excitatory postsynaptic currents
increased miniature inhibitory postsynaptic current amplitude
abnormal long-term depression
Availability Mouse Genotype
Tg(ACTB-Eif4e)#Ppp/0
Tg(ACTB-Eif4e)#Ppp/?

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory